A Map of Mouse Brain Metabolism in Aging
The first atlas of metabolites in the mouse brain has been published by a team led by UC Davis researchers. The dataset includes 1,547 different molecules across 10 brain regions in male and female laboratory mice from adolescence through adulthood and into advanced old age. The work is published Oct. 15 in the Nature Communications. The complete dataset is publicly available at https://mouse.atlas.metabolomics.us/.
"This is the largest metabolome analysis available on the brain, worldwide. It covers 1,547 identified metabolites, enabling analysis of many chemical conversions for energy, neurotransmitters or complex lipids in the brain,” said Professor Oliver Fiehn, director of the West Coast Metabolomics Center at the UC Davis Genome Center and senior author on the paper.