Established in 2003, the UC Davis Genome Center uses state-of-art-technologies to understand how the heritable genetic information of diverse organisms functions in health and disease. The combination of cutting-edge research facilities, diverse service cores, and talented staff make the Genome Center a world class facility for genomics research and training.
Research that makes a difference
A sample of questions being addressed by the UC Davis Genome Center faculty and their collaborators:
- How do variations in the human genome affect the risks of diseases such as cancer, coronary artery disease, and autism?
- Do infection, diet, or stress serve as environmental triggers of Type 1 diabetes?
- What novel, useful organisms will be discovered by sequencing microbes from extreme environments?
- Can characterization of the small molecules in algae lead to new biofuels?
- How can we control diseases of important food crops?
- How can plants be modified to increase their productivity and quality?
- What changes can we make to proteins to enhance their performance?
- Can we model and predict life’s basic processes?
- How can we glean useful information from vast datasets?
Here are just some of the recent highlights involving people and projects at the Genome Center. Please see the news page for a full list of all news items.
Recent publication: Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal
A recent publication from Lemay et al. unexpectedly showed subject-specific differentially expressed genes in response to eating a fatty meal, as shown by a whole blood transcriptome analysis.
Genetic variation and temperature affects hybrid barriers during interspecific hybridization
Bjerkan et al. 2019. The Plant Journal.
This paper provides evidence that post-zygotic hybridization barriers can be affected by both genetic and abiotic factors. Read more...
Congratulations to Brenna Henn for receiving an NIH Maximizing Investigators’ Research Award (MIRA) grant for Early Stage Investigators for $1.9 million. The project is entitled “Improving Inference of Genetic Architecture and Selection with African Genomes.” Read more...
Recent publication: scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data
A recent publication from Li and Quon describes a new detection method, called scBFA, to model both
Recent publication: The alternative reality of plant mitochondrial DNA: One ring does not rule them all
A new publication by Kozik et al. in PLOS Genetics has illustrated that the mitochondrial genome of lettuce is fluid and dynamic, with multiple sequence arrangements. The authors point out that the misconception of a circular mitochondrial genome in plants, which is often described ... Read more...