Biologists and biomedical investigators need metabolomic data but must rely on the services from metabolomic service providers in Universities or private companies. Interests in metabolomics services are very diverse, ranging from PK/PD to untargeted metabolomics, and from flux analysis to absolute quantifications of pathway intermediates. How can metabolomic service cores manage such demands and expectations with limited resources? At UC Davis, we have run metabolomics services for the past 16 years. In this short course, we will provide a strategic overview on how to deploy tools, spot and fill bottlenecks, assess your core's capacity, scale up from small studies to 1000s of samples and provide high-throughput / high-quality services in a time and cost-efficient manner. We discuss how to consult with clients, how to provide educational resources, and how to manage staff and budgets. Recognizing that there is no one-size-fits-all strategy, we will survey measures on how to best engage your research community to utilize metabolomics services.