Recent publications from the Genome Center
scAlign: a tool for alignment, integration, and rare cell identification from scRNA-seq data
Johansen and Quon. 2019. Genome Biology, 20: 166
The authors present scAlign, a deep learning-based method for single cell RNA sequencing. Read more
Precision nomenclature for the new genomics
Lewin et al. 2019. Giga Science, 8(8)
Lewin et al. offer distinct terms for modern-day nomenclature C-scaffold and scaffotype to allow scientists to clearly and without confusion classify genome assemblies. Read more
Assessment of protein model structure accuracy estimation in CASP13: challenges in the era of deep learning
Won et al. 2019. Proteins
The authors assess the accuracy of scoring models of protein structure prediction using CASP. Read more
Association of lactase persistence genotypes (rs4988235) and ethnicity with dairy intake in a healthy U.S. population
Chin et al. 2019. Nutrients, 11(8)
The authors investigate lactose intolerance and ethnicity and whether this affects dairy consumption in the U.S. Read more
A new mechanism for translational control in plants
Miller and Dinesh-Kumar The FEBS Journal.
Miller and Dinesh-Kumar describe what occurs when the cap-binding protein elF4E, which binds the 5' cap structure (m7G) on mRNA and recruits other translation factors to bring the ribosome mRNA, is negatively regulated. Read more
Perspective: dietary biomarkers of intake and exposureâexploration with omics approaches
Maruvada et al. 2019. Advances in nutrition, nmz017
The authors provide perspective on using metabolomics and bioinformatics to provide new opportunities to develop dietary biomarkers. Read more
An integrated chromosome-scale genome assembly of the Masai giraffe (Giraffa camelopardalis tippelskirchi)
Farre et al. 2019. Giga Science, 8(8)
This paper presents the first chromosome-scale genome assembly for the Masai giraffe, which is a valuable resource for conservation of the species. Read more